Last month the guys over at Top Notch Themes published their free 29 page Ubercart guide. The demonstrate what you need to know so that you can get the most from your Ubercart shopping cart once you've actually added it to your Drupal installation. They go into some pretty good detail about how to best configure the system and which modules to use (hint: most are in the iSite Essentials).
Major topics that are included as part of the guide are:
I'm currently in the process of developing a little side project for Kristen and their information has already saved me countless hours trying to determine how to best configure all the options.